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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPTY2D1 All Species: 24.24
Human Site: S403 Identified Species: 44.44
UniProt: Q68D10 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q68D10 NP_919261.2 685 75546 S403 V P R R Q N G S S S S G P E R
Chimpanzee Pan troglodytes XP_508321 684 75407 S403 V P R R Q N G S S S S G P E R
Rhesus Macaque Macaca mulatta XP_001082108 684 75599 S403 V P K R Q N G S S S S G P E R
Dog Lupus familis XP_534086 793 86791 S514 V P R R Q N G S S S S G P E R
Cat Felis silvestris
Mouse Mus musculus Q68FG3 682 74799 S403 V P R R Q N G S S S S G P E Q
Rat Rattus norvegicus XP_002725626 681 74519 S403 V P R R Q N G S S S S G P E Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517926 644 69600 P361 S A G G A Q R P S G E Q G L K
Chicken Gallus gallus XP_421015 633 66869 H358 S S L K K P V H T K P G N A A
Frog Xenopus laevis Q6NU13 800 83727 P512 G A S G S G K P T G A P G A S
Zebra Danio Brachydanio rerio Q6DGN6 629 69420 S365 A K S S I S G S C P P G A A R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IMP6 581 65683 R324 N R M E P N G R I P K L N Q A
Honey Bee Apis mellifera XP_395689 579 67372 N322 R N K L G N V N N K E A S I V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793115 639 72247 G356 S R P G E R Q G E R P G G R I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 96.7 73.6 N.A. 80.5 82.1 N.A. 55.6 47.8 43 42.7 N.A. 28.3 23.2 N.A. 24
Protein Similarity: 100 99.5 98.5 78.8 N.A. 89.9 90.3 N.A. 66.5 58 56.6 58.6 N.A. 44.2 41.6 N.A. 39.8
P-Site Identity: 100 100 93.3 100 N.A. 93.3 93.3 N.A. 6.6 6.6 0 26.6 N.A. 13.3 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 13.3 26.6 13.3 33.3 N.A. 20 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 16 0 0 8 0 0 0 0 0 8 8 8 24 16 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 8 8 0 0 0 8 0 16 0 0 47 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 8 24 8 8 62 8 0 16 0 70 24 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 8 0 0 0 0 8 8 % I
% Lys: 0 8 16 8 8 0 8 0 0 16 8 0 0 0 8 % K
% Leu: 0 0 8 8 0 0 0 0 0 0 0 8 0 8 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 8 0 0 0 62 0 8 8 0 0 0 16 0 0 % N
% Pro: 0 47 8 0 8 8 0 16 0 16 24 8 47 0 0 % P
% Gln: 0 0 0 0 47 8 8 0 0 0 0 8 0 8 16 % Q
% Arg: 8 16 39 47 0 8 8 8 0 8 0 0 0 8 39 % R
% Ser: 24 8 16 8 8 8 0 54 54 47 47 0 8 0 8 % S
% Thr: 0 0 0 0 0 0 0 0 16 0 0 0 0 0 0 % T
% Val: 47 0 0 0 0 0 16 0 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _